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August 2002

Feature

 


The University-Industrial Complex: A threat to the public funded institution?

1,2Dr Alex Valentine & 1,3 Dr George Claassen
1 Dept of Journalism, University of Stellenbosch
2 Department of Botany, University of Stellenbosch
3 Science & Technology Editor, Die Burger

REMEMBER WHEN science fiction portrayed certain areas of research as dabbling in the creation of doomsday monsters? Well, closer to science fact is that over the past 20 years, research in science has insidiously given rise to a formidable commercial creature: University-Industrial Complex. This beast is the offspring of the commercialisation of science at universities and may doom many of the relevant characteristics of public funded academic institutions.

Amongst some academics there is growing concern about the commercialisation of science at universities. The traditional roles of public funded institutions is seen as being: the conscience and critics of society, the education of new generations and the pursuit of knowledge or truth, free from market forces or government agendas. The university-industrial complex, amid all its widely-touted financial benefits, appears to threaten these characteristics that define a good university. So what is university-industrial complex? It can be defined as the intimate ties that exist between universities and industrial enterprises, to the extent that the public accountability of the academic institution is undermined for profit.

Concerns about the commercialisation of universities began to emerge during the debate of the late 1970's about the safety issues surrounding the then-new recombinant DNA technology. The concern centered on the potential influence of the commercialisation of university research on the university as an institution (Kenney, 1998). Contractual relationships between academia and industry create loyalties, or at least vested interests, that restrict a university's freedom of expression. For example, Nike's funds from the Universities of Michigan, Oregon and Brown were withdrawn because of student protests against the company's factory labour practices in developing countries (Warde, 2001). Freeport MacRonan funds a Chair of Environmental Studies at the University of Tulane yet is accused of environmental misconduct in Asia, and The Gap supports the University of California's Berkeley Business School, which uses the company's case studies in its academic courses (Press and Washburn, 2001).

Nowhere else has the growth and influence of the university-industrial complex been more visible than in the USA, as illustrated by the biotechnology industry and its related pharmaceutical applications. The techniques and products of the biotechnology industry have been commercialized more than any other academic technology (Kenney, 1998).

Knowledge developed by non-profit academic institutions does not lend itself readily to commercialisation. However, the past few decades have seen a number of key decisions that have catalysed the commercialisation of academic research and the growth of the university-industrial complex. In 1974 the USA National Institutes of Health consented that universities be allowed to patent and license their genetic engineering research, freeing government-sponsored research from any public claims of ownership and thus fostering the privatisation of government-funded academic research. (Kenney, 1998). The 1980 Bayh-Dole act of the US Congress empowered universities to patent and commercialise state-funded research at a time when the US economy was weakening relative to that of Japan, creating a climate in which commercial forces increasingly dictated universities' educational and academic missions and ideals. It also led to a massive increase in funding to universities. Between 1980 and 1998, funding for research at US universities increased annually by 8%, reaching a staggering 1.9 billion US dollars in 1997 (Press & Washburn, 2001). As with all new technologies, it is unlikely that commercial finance was readily available from the start. Where did the funding initially come from?

The commercialisation of university research in the USA was initially funded by venture capital firms that arose after the Second World War and have since grown to a multi-billion dollar financial sector that supports high-risk, high-reward ventures. Emboldened by the rewards of financing the high-technology research that generated companies such as Apple Computers, Sun Microsystems, Lotus and Intel, these firms were primed to gamble on another untried technology. Their locations near university campuses with strong electronic engineering faculties placed venture capital firms conveniently close to the molecular biology laboratories at which many of the early advances in recombinant DNA technology were made (Kenney, 1998; Wilson, 1985; Florida & Kenney, 1990).

One of the earliest biotechnology firms in the USA was Genentech, founded by venture capitalists in 1976. The impetus for Genentech's early commercial research was supported by the infrastructure of its scientific partner, the University of California at San Francisco. Genentech's commercial success and public prominence were ensured by its cloning of a human insulin gene into a micro-organism and the subsequent licensing of this procedure to the largest insulin producer in the USA. Despite the steady growth of the biotechnology industry, the recruitment of top scientific staff from universities was surprisingly difficult, prompting venture capital firms to create scientific advisory boards upon which scientists from prominent universities could sit without compromising their tenured positions (Press & Washburn, 2001)

The commercialisation of biological research has also broadened dramatically in recent decades. In the 1970's and 1980's, recombinant DNA and monoclonal antibodies were the main biotechnologies subject to commercialization, but more recently the health and pharmaceutical industries have capitalized on biological metabolites, including, liposomes, antisense molecules, peptides, carbohydrates and stem cells.

Increased commercial funding of universities in the mid-1980's led to the formalisation of the spirit with which biological materials were exchanged. University laboratories in the USA required researchers to complete biological material supply forms to gain access to biological materials. In turn, universities became more aggressive in patenting and protecting their intellectual property, leading to greater caution on the part of large multinational firms that had initially signed very lucrative agreements with universities in order to gain access to their intellectual property.

The university-industrial complex may compromise academic standards of research. According to an editorial in the journal Nature (2001), recent publications in biomedical journals show that company-sponsored researchers more frequently report results favourable to company products than the reverse, implying bias. Before the arrival of the university-industrial complex, the culture of science could be likened to communism, where intellectual property was freely exchanged and shared and knowledge was generated for the public good. With industry-sponsored research, there was a shift towards confidentiality and the practice of allowing the sponsors to manipulate the manuscripts before publication to serve the interests of the companies. US-based examples include 35% of researchers in engineering which allow their sponsors to manipulate their manuscripts and a large pharmaceutical company, who removed passages from a draft publication that their drug may cause strokes and heart failure.

Furthermore, companies may attempt to curtail academic freedoms or institutionalise their influence at universities. For example, the biotechnology company Norvatis, is paying the University of California at Berkeley 5 million US dollars per year for plant research and granting the university access to company databases. In exchange for seats on university and departmental research committees and first negotiating rights of up to 30% of all academic discoveries made by the supported departments. Furthermore, Norvartis has prevented the academics from discussing this deal, which is an encroachment on academic freedom (Nature 2001, Press and Washburn, 2001).

Another serious impact of the university-industrial complex is the price-tagging of science departments, based on how much industrial money they can attract and the downsizing of humanities faculties. Hunter Rawlings (1999), the President of Cornell University, recently argued that the new tendency to be driven by financial considerations can lead to short-sighted favouring of research fields that show commercial potential and neglect of those that do not. Humanities disciplines provide serious critique on the influence of science on global culture, enlarge our worldview and act as the keepers and conveyors of culture in a democratic society. Since the time of Socrates, the humanities have been catalysts for social change, providing society with a critical spirit and a mind set upon argument (Rawlings, 1999). Loss of the humanities would come at great cost to global society and thus to universities themselves.

Should the role of the university be redefined to keep up with the realities of global economic changes? Bill Readings (1998) argues that the university has outlived the purpose defined for it 200 years ago, when it was seen as the guardian of national culture. Perhaps South African universities are following the trend described by Readings (1998) for the USA, where universities are now operating as autonomous bureaucratic institutions and do not care much about the values of specific ideologies. Instead, they are aimed at generating and exchanging information that is useful to the corporations and government, those who call the tune for paying the piper.

The implication of this view is that fundamental research might be curtailed in favour of more short-term commercially viable options. The danger of this can be seen in the case of the Nobel Prize winner Paul Berg, whose fundamental research at Stanford University laid the groundwork for the splicing of DNA and consequently was one of the main thrusts behind the rising biotechnology industry. However, shortly after his innovate finding, he discovered that a scientist at a large pharmaceutical company had been pursuing the same research, but was prevented by the company from taking the work beyond a certain point. Berg highlights that this example represents the limitations of corporate research (Press and Washburn, 2001). Innovative discoveries are more likely to be published if they arise from fundamental academic research that is free of industrial obligations.

One should recognise that these impacts on academic institutions may not be global, at least not yet. There are differences that exist on the campuses within the developed economies such as Europe and North America. Despite this difference, it may also seem that the growth of the University-Industrial Complex sharply follows the divide between universities from developed and developing economies. But with shrinking budgets in developing economies, this difference might soon change. In South Africa, with the dwindling size of government coffers for fundamental research, there has been an increasing trend to encourage academic research to form tighter bonds with industry and to commercialise research. This is also evident in the rapid increase of intellectual property offices at local universities. Although several years behind for the phenomenon in the USA, the benefit of such a lag is that we can observe the potential dangers and avert similar conflicts of the history yet to come.

 

References cited

Eyal Press and Jennifer Washburn, The Kept Univeristy, The Atlantic Monthly, March 2000, Volume 285, 3, 39-54

Bill Readings, The university in ruins, Harvard University, 1998

John Wilson, The New Venturers: Inside the high stakes word of venture capital. Reading, Mass., Addison-Wesley, 1985.

Ibrahim Warde, For sale: US academic integrity. Le Monde Diplomatique, March 2001

Richard Florida and Martin Kenney, The breakthrough illusion, New York : Basic Books, 1990

Martin Kenney, Biotechnology and the creation of a new economic space. In: Private science: Biotechnology and the rise of molecular sciences A. Thackray (ed) Philadelphia, University of Pennsylvania Press

Nature, 11 January 2001, Volume 409, nr 6817

Hunter R. Rawlings III, President Cornell University, The role of humanities in a research university. December 6, 1999.




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