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October 2002

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Computer viruses vs biological viruses 

MRC News

Computer viruses and 'real' biological viruses are bugs that make our lives difficult. According to molecular microbiologist Dr Trudy Wassenaar, they share more than a few common characteristics - and these similarities can help us to understand and control both better. Find out why computer viruses can be likened to STDs. 

Dr Wassenaar, currently an MRC-funded Distinguished Visiting Scientist based with Prof. Al Lastovica (Department of Medical Microbiology, University of Cape Town), says that computer programmers and biomedical clinicians have a lot more in common than they might think. Like viruses, for instance.

"Our knowledge of biological viruses can help identify the routes that virus programmers have taken, and will take, in due course. But less obviously, the Internet is a real-time evolutionary model of infectious diseases for clinicians to study," she says.

Striking similarities

Both biological viruses (living organisms made up of DNA or RNA inside a protein coating) and their cyberspace counterparts (computer programs written by mean-minded computer boffins) parasitise on their host and can only replicate when inside that host.

"Biological viruses enter their host through an opening after passively being breathed in, swallowed or via direct contact. Virtual viruses also enter their 'host' passively when you insert an infected disk or open an infected e-mail attachment. Similarly to a biological virus which has to have the correct host and tissue specificity to gain a foothold - a horse virus wouldn't make a human being sick - a computer virus has to be compatible with the system to gain a foothold."

"The damage these viruses do, is also similar. Biological viruses replicate at the cost of the host - damage can include pain, suffering and even death. Computer viruses slow down the computer - files can become inaccessible and even lost, and sometimes the complete hard disk gets damaged," Dr Wassenaar explains.

Worms and viruses

The term 'computer virus' can actually mean one of three things: a virus (a program that implants a version of itself in any program it can modify and then spreads to files within a computer, or with user interaction like sharing infected disks, between computers), a worm (a harmful program that spreads copies between computers in a network, such as the Internet, without user interaction) or a Trojan horse (a program that makes a computer available to non-authorised users).

A virus, worm or Trojan horse can (like HIV) be latent, only to become active after a certain period. This is called a 'logic bomb'. These three classes of computer malware can also have hundreds of variants or several slightly modified versions, which parallel microbial diversity.

Spreading across boundaries

Dr Wassenaar draws some interesting parallels when it comes to the dissemination or spread of viruses. "Because worms spread without any user interaction, they are like socially transmitted diseases such as influenza, that have the potential to infect everyone susceptible. In contrast, computer viruses are like sexually transmitted diseases. Their spread (through sharing infected diskettes) is like that of STDs, whose spread is related to specific behavioural practices. 'Logic bombs' are like HIV, because they are only activated at a later date," she explains.

As with biological viruses, simple hygiene measures can protect you against computer viruses. "Just as people would wash hands frequently, avoid exposure to people with colds, or use condoms to protect against infectious diseases, computer users should mistrust (and thus not open) files received through unexpected channels or with unknown extensions or subject lines, request confirmation from the sender before opening attachments, and regularly back up hard disks to reduce the risk of losing data," Dr Wassenaar says.

Fortunately, we do have anti-virus programs. "But virus protection programs are only as good as the last virus recognized, providing only partial protection at best," she warns.

Auto-immune diseases

When your body's immune system runs out of control and starts damaging itself, this is known as an auto-immune disease. Similarly, computers can also fall prey to such diseases. "Recently, a 'warning' turned out to be a not-so-harmless hoax. The hoax warning stated that certain files were infected by a computer virus. Heeding the warning, unsuspecting computer users removed the affected utility files from their computers' operating system. Fortunately, this time it only turned out to be a mild nuisance, because the computers weren't permanently damaged. But a more malignant hoax could be as devastating to computers as some auto-immune diseases are to humans," Dr Wassenaar says.

Biological viruses also 'steal' virulence genes from other viruses and become more malignant. This also happens in the case of computer 'malware'. "Just a week after the September attack against the United States, a highly dangerous worm called Nimda was released. This combined the most powerful strategies of two other worm programs, and spread more rapidly than any other previous worm. Clicking on the subject line of an infected e-mail (to delete it, for instance) itself activated the worm. But because this worm was so fast moving, so potentially dangerous, people saw it right away and responded, so slowing its spread," she explains.

This is similar to the biological world, where with outbreaks of haemorrhagic fevers such as Ebola, the immense threat of high contagion and lethality prompts effective measures to rapidly recognise outbreaks and prevent pandemics.

What can we learn?

Dr Wassenaar thinks we can learn from biology. Nature has evolved immunity that protects plants and animals against a broad range of pathogens. "In any human being's gut there are native microflora that render partial protection against infections. Could we perhaps design 'benign' computer viruses, that could spread through the Internet in an uncontrolled manner, automatically block entries for malign viruses, update our antiviral programs or inactivate existing viruses? Microbiologists can help programmers to combat viruses - computer immunity may be expensive, but eventually we'll have to accept the risks and costs involved," she says.

But, conversely, the study of computer malware may help to control infectious disease emergence. "The Internet is a good model to study the development of infections and how they spread through our increasingly small world. The speed of virtual pathogen evolution makes it possible to follow the process of mutation and selection real-time," Dr Wassenaar argues.


More information

Dr Wassenaar has a Ph.D. in Natural Sciences and is a trained molecular (micro)biologist. Her major field of work is bacteriology (enteric diseases) and since 1999 she has worked as a research consultant for her own company, Molecular Microbiology and Genomics Consultants. In addition to consulting on fundamental and applied research for Academia (including UCT) and governmental agencies, Dr Wassenaar is also the Curator of the Virtual Museum of Bacteria. "It was the combination of a genuine interest in infectious diseases, an overload of virus-generated e-mails, and a creative mind, that resulted in the virus comparison," she says. An article was published in Emerging Infectious Diseases (2002; 8: 335-336). More information on computer viruses can be obtained at http://www.symantec.com, http://www.mcafee.com, http://www.f-secure.com and http://www.Vmyths.com.


This article courtesy MRC News

 




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