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January 2004

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Out of Africa: TWOWS' first graduate

Helping young women scientists in the south fulfill their potential

With the help of TWOWS fellowships, talented and dedicated women scientists, despite their small numbers, are slowly helping to build the scientific capacities of their countries - and, in the process, boosting their own career prospects and helping to advance the economic and social well-being of their nations too. Meet Dr Osowole, TWOWS first graduate.

TWOWS

Aderoju OsowoleThe Trieste-based Third World Organization for Women in Science (TWOWS), which was launched in 1993 under the auspices of the Third World Academy of Sciences (TWAS), fosters cooperation among eminent women scientists from the South and to help young women who have displayed scientific potential to advance their careers.

The TWOWS young women scientists fellowship programme enables promising female students from sub-Saharan African nations and other Least Developed Countries (LDCs) to apply for grants to support postgraduate training leading to a PhD.

To date, TWOWS has awarded post-graduate fellowships to over 150 young women scientists from 37 countries.

Aderoju Osowole from Nigeria, has now become the first young woman scientist to graduate from the scheme.

Hooked on science

Despite the inhospitable learning environment she faced, Aderoju Osowole became hooked on science at an early age.

Aderoju grew up in Ibadan in southwest Nigeria. During the first year of her secondary school education, Aderoju was introduced to such classic scientific demonstrations as the 'popping' sound created when a lighted splint is inserted into a test tube containing hydrogen, and the decolouration of green plants left to grow in the dark. "These observations," says Aderoju, "challenged my mind as a young girl and convinced me that I should study science."

After leaving high school, Aderoju went on to study chemistry at the University of Ibadan, gaining her bachelor's degree in 1990 and master's in 1993. These milestones were followed by her enrolment, in 1997, in the university's PhD programme to study, as the title of her dissertation opaquely describes, the "synthesis, physicochemical and biological properties of cobalt, nickel and copper complexes of various substituted
beta-ketoamines and their adducts."

In simpler terms, Aderoju began to investigate the characteristics of molecules containing both organic and inorganic components and, more specifically, how these molecules could be developed for use in such bio-industrial processes as the inhibition of corrosion caused by sulphate-reducing bacteria. Several of the compounds also showed potential antibiotic activity against such food-poisoning bacteria as Staphylococcus aureus and Escherichia coli.

During the early stages of this research, Aderoju realized that she would not be able to complete her work at Ibadan because equipment critical for her research - for example, a spectrometer to measure the mass and relative concentrations of atoms and molecules - was not available. A senior instructor, Gabriel A. Kolawole, who has since moved on to the Department of Chemistry, University of Zululand, Republic of South Africa, suggested that she might be able to overcome this obstacle by applying to the Third World Organization of Women in Science (TWOWS) fellowship programme for assistance.

Aderoju submitted her application in 1998 and she received notification of her acceptance to the programme later that same year. TWOWS fellowship funds enabled her to travel to the Indian Institute of Science's Department of Inorganic and Physical Chemistry in Bangalore, India - a recognized centre of excellence in her line of research. Aderoju spent one year of her four-year research programme in India.

Hi-tech in India

"At Bangalore, I was able to carry out the micro- analysis and infrared and mass spectroscopy analyses that I needed to complete my PhD research," explains Aderoju. "Together, mass spectroscopy and the microanalysis of carbon, hydrogen and nitrogen enabled me to determine the correct proportions of these elements in my chemical reactions and their products. Moreover, by analysing the infrared spectra, which was again made possible by the equipment in Bangalore, I could decipher whether the metal atoms I was interested in were linked to the organic molecules via carbon-oxygen bonds or carbon-nitrogen bonds, which is essential for predicting the behaviour of the compounds." While at the Indian Institute of Science, Aderoju also enjoyed access to libraries stocked with up to- date journals and equipped with state-of-the-art information search and retrieval systems - critical intellectual resources for every research project.

Under the supervision of Varadachari Krishnan (TWAS Fellow 1996), whose research has focused on the biochemistry of cellular processes, Aderoju was also able to use the facilities and expertise available at Bangalore to venture into a new research area. She began to study porphyrins - organic compounds that, in the plant kingdom, combine with such metals as magnesium to produce chlorophyll, the molecule responsible for trapping light energy and converting it into chemical energy. In the animal kingdom, porphyrins combine with iron, to produce haem - as in the blood protein, haemoglobin, which absorbs oxygen in our lungs and transports and releases this essential constituent of life to our body's cells. Porphyrins, in brief, act as electron transport agents within cells and, for this reason, could have great potential as nanocomponents in such electronic devices as computer hardware and mobile telephones.

Aderoju obviously used her time in India well and, on returning to Nigeria, was able to complete her thesis. She was awarded her doctorate degree, becoming the first scientist to graduate from the TWOWS fellowship programme.

Back in Nigeria

Osowole now works on bacteriaShe is now back in Nigeria where both graduate and postgraduate students attend her lectures and benefit from the time she spent in India. She is also continuing her research on the chemistry of biologically active molecules that could find uses as catalysts and antimicrobial agents. In particular, Aderoju has identified a cobalt compound that, at optimal concentrations, kills 100 percent of Streptococcus pyogenes bacteria, the causal agent of tonsillitis, within an hour.

She admits that the lack of facilities in Nigeria impedes her progress. Her positive experience with the TWOWS fellowship, however, has given her the confidence to seek another fellowship that would allow her to go abroad to further characterize the complex organometal compounds she is interested in and to continue to explore their potential industrial applications.

A recent World Bank study covering 192 countries shows that human and social capital is responsible, on average, for about two-thirds of a nation's gross domestic product. If women are unable to fulfil their academic promise, one-half of a nation's human resource potential is compromised. In today's world, such a loss carries serious consequences for a nation's social and economic well-being.

In many developing countries (and developed countries as well), science jobs, especially at higher levels, tend to be male-dominated. In southern Africa, for example, women account for about 25 percent of science students, 10 percent of university teachers, and less than 1 percent of the total number of tenured science professors. This makes Aderoju - and other women like her - true pioneers in their fields.

Aderoju readily admits that she sees herself as a role-model for other young women. "Female scientists," she says, "must excel beyond the artificially imposed limits set for them by society, which often still believes that women cannot attain the same level of achievement as their male counterparts. I attribute my own success to my strong determination, hard work and perseverance." Aderoju is now using her experience and knowledge to help other young women students at the University of Ibadan and elsewhere by giving them moral support and imparting skills and ideas through collaborative research.


More information:

Article by TWAS Newsletter

For more on TWAS and TWOWS see here.

 

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