Jobs in Biological Sciences

Discipline Position Country Info
Bioprocess Engineering - Microbial Cell Strength Postdoctoral  South Africa LINK
Bioprocess Engineering - Microbial Flux analysis Postdoctoral  South Africa LINK
Genetics, Biometrics Senior lecturer/ lecturer South Africa LINK
Nanotechnology - sensors Postdoctoral South Africa LINK
Virus-host cell interactions Phd, MSc South Africa LINK
Microbial Biotechnology and Metagenomics Several: Senior lecturer, postdoctoral, PhD and MSc fellowships South Africa LINK
Molecular Biology Postdoctoral South Africa LINK
Molecular chaperones and stem cells PhD, MSc position South Africa LINK
Health sciences  Protocol Coordinator Uganda LINK
Receptor biology
Biochemistry
Postdoctoral South Africa LINK
Applied Microbiology MSc, PhD and Postdoctoral positions South Africa LINK
Biocatalysis/ Bioprocess Engineering Several: Postdoctoral, Scientific officer, Contract researcher South Africa LINK
Biochemistry, Cellullosome MSc, PhD, Postdoctoral South Africa LINK
Electrochemistry/Biosensors/
Nanotechnology
MSc, PhD and postdoctoral South Africa LINK
Medical Biosciences 2 MSc positions South Africa LINK
Anticoagulant/antithrombotic and antidiabetic agents Postdoctoral South Africa LINK
Receptor Biology Postdoctoral South Africa LINK
Molecular biology/wildlife MSc South Africa LINK
Virology PhD South Africa LINK
Catalysis Postdoctoral South Africa LINK
Epigenetics, genomics, proteomics and bioinformatics PhD and MSc bursaries South Africa LINK
Biotechnology PhD bursaries South Africa LINK
Bioinformatics Junior lecturer/Lecturer South Africa LINK
Forestry/ forest products MSc, PhD, postdoctoral South Africa LINK
Enzymology/molecular biology MSc, PhD bursaries South Africa LINK
Biochemistry MSc South Africa LINK
Phylogeography of Invertebrate species MSc or PhD South Africa LINK
Molecular and cellular biology Masters South Africa LINK
Genetics, insects MSc and PhD opportunities South Africa LINK
Conservation genetics (golden mole) Masters South Africa LINK
Structural biology Masters South Africa LINK
Chromatin Structure and the Regulation of Gene Expression Postdoctoral fellowships South Africa LINK
Bioprocess Engineering PhD and postdoctoral research South Africa LINK
Biocatalysis/Bioremediation Postdoctoral research South Africa LINK

 

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University of Cape Town

Postdoctoral Fellowship 
Microbial Cell Strength

  • A postdoctoral fellowship is being offered in the Department of Chemical Engineering in the area of bioprocess engineering, specifically the study of microbial cell strength in relation to both process stress and product recovery:
  • The fellowship is available from May 2008 for one year. It may be renewable for up to two further years, contingent on satisfactory progress and availability of funds.
  • The fellow must hold a PhD degree in Microbiology or Chemical Engineering that has been granted within the past 5 years or the candidate must provide satisfactory evidence that the PhD Thesis has been submitted for examination.
  • The candidate may not have held previously any permanent professional post, specifically as an academic.
  • Applicants are sought with specific experience in a selection of the following areas:
    o Microbial cell strength analysis
    o Microbial response to process stress
    o Microbial product recovery
    o Microbial modelling
  • The fellow will be expected to conduct a research project centred on analysis of microbial cell strength in relation to biological response to process stress or biological product recovery or both. Further, as part of their professional training, the fellow will involve him or herself in the supervision of research students in agreement with the supervisor, assist in transfer of techniques within the laboratory and co-author journal publications on research to which he / she contributes.
  • The fellow must not be registered for any degree studies while he/she holds the fellowship. He/She will, however, receive a student card in order to access UCT facilities such as the libraries.
  • The fellow will not be regarded as an employee of the University. No benefits are attached to the fellowship of R 120 000 per annum. An individual application to the South Africa Revenue Services for tax-exemption is made by the university on behalf of the successful candidate.
  • The successful applicant must be prepared to comply with the University of Cape Town's approved policies, procedures and practices for the postdoctoral sector.


Applications to be sent to;
Bev Bailey
PA to Professor Sue Harrison 
Beverley.Bailey@uct.ac.za
  
Tel: (021) 650 4021

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University of Cape Town

Postdoctoral Fellowship

Metabolic Flux Analysis

A postdoctoral fellowship is being offered in the Department of Chemical Engineering in the area of bioprocess engineering, specifically metabolic flux analysis:

  • The fellowship is available from April 2008 for one year. It may be renewable for up to two further years, contingent on satisfactory progress and availability of funds.
  • The fellow must hold a PhD degree in Microbiology, Molecular Biology, Biochemistry or Chemical Engineering that has been granted within the past 5 years or the candidate must provide satisfactory evidence that the PhD Thesis has been submitted for examination.
  • The candidate may not have held previously any permanent professional post, specifically as an academic.
  • Applicants are sought with specific experience in a selection of the following areas:
    o Metabolic networks 
    o Metabolic flux analysis
    o Biochemical systems theory
    o Multi-reaction modelling
    o Microbial systems
  • The fellow will be expected to conduct a research project centred on metabolic flux analysis and metabolic modelling of bacterial or algal systems. Further, as part of their professional training, the fellow will involve him or herself in the supervision of research students in agreement with the supervisor, assist in transfer of techniques within the laboratory and co-author journal publications on research to which he / she contributes.
  • The fellow must not be registered for any degree studies while he/she holds the fellowship. He/She will, however, receive a student card in order to access UCT facilities such as the libraries.
  • The fellow will not be regarded as an employee of the University. No benefits are attached to the fellowship of R 120 000 per annum. An individual application to the South Africa Revenue Services for tax-exemption is made by the university on behalf of the successful candidate.
  • The successful applicant must be prepared to comply with the University of Cape Town's approved policies, procedures and practices for the postdoctoral sector.


Applications to be sent to;
Bev Bailey
PA to Professor Sue Harrison
Beverley.Bailey@uct.ac.za
 
Tel: (021) 650 4021

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Stellenbosch University

Genetics
Biometry

Senior Lecturer/Lecturer
(Ref. 02SV61)

The Biometry Division in the Genetics Department is responsible for the teaching of Biometry as a generic skill to all undergraduate and postgraduate students in certain fields of study of the Faculty of AgriSciences. The aim of the teaching is to equip our graduates with specific quantitative expertise and skills. This post requires a person with specialised knowledge of statistical methodology commonly used in biological experimental research, as well as an interest in Biology, Agriculture and/or Forestry.

Duties: Teaching undergraduate and postgraduate students; developing and evaluating course material; postgraduate supervision; participating in research projects of the Genetics Department and/or the Faculty of AgriSciences; research in the chosen field of specialisation; ongoing reporting of research results through publications; congress presentations; participating in activities at departmental as well as faculty level; performing administrative duties.

Requirements: Senior Lecturer - Doctorate in Biometry/Statistics (or an equivalent qualification). Lecturer - Master's degree in Biometry/Statistics (or an equivalent qualification). Senior Lecturer/Lecturer - Knowledge of statistical methodology used in the agricultural sciences; a suitable publication profile for the post level being applied for; experience in the use of Excel and SAS for data analysis; experience in the applied biological sciences; excellent communication and language skills; ability to teach in Afrikaans and/or English; working knowledge of Afrikaans as well as English.
Recommendations: Tertiary teaching experience; experience in the field of experimental design, bioinformatics or population genetics; research experience; knowledge of other statistical software and/or programming languages.
Commencement of duties: 1 May 2008 or as soon as possible thereafter
Closing date: 20 March 2008
Enquiries: Prof. L. Warnich on +27 21 808 5888 or Ms A. Sadie on +27 21 808 5836

Prospective candidates are requested to submit a concise proposal with their applications as regards their envisaged contribution towards enhancing teaching, research and service delivery, should they be appointed.

Applicants must clearly indicate the post level for which they would like to be considered.

The University will consider all applications in terms of its Employment Equity Plan, which acknowledges the need to diversify the demographic composition of the staff corps, especially with regard to the appointment of suitable candidates from the designated groups.

The University reserves the right not to make an appointment.

A competitive remuneration package and excellent service benefits are attached to this position. For further details, contact +27 21 808 4829.

Obtain the prescribed application form on our homepage at http://www.sun.ac.za/applicationforms  or by e-mailing ldavids@sun.ac.za  or contacting +27 21 808 2369.

Completed application forms, accompanied by a comprehensive curriculum vitae which includes the names and contact details of at least two referees, must be forwarded via e-mail to ldavids@sun.ac.za  or to The Manager: Personnel Provisioning & Planning, Stellenbosch University, Private Bag X1, Matieland 7602, South Africa or fax +27 21 808 2484.

Applicants should request their referees to forward confidential reports by the closing date direct to the same address.

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Rhodes University

Department of Biochemistry, Microbiology & Biotechnology

MSc/PhD Position: Picornavirus-host cell interactions

MSc and PhD positions will be available in the beginning of 2008 for students who have an interest in virus-host interactions. The project is funded by the NRF, and will be supervised by Dr Caroline Knox in the Department of Biochemistry, Microbiology & Biotechnology, Rhodes University. Candidates should have the relevant qualifications, and preferably, practical experience in molecular biology, protein biochemistry and cell biology. To comply with the funding conditions, candidates need to be South African citizens or permanent residents. If you are interested, please email your full CV to: caroline.knox@ru.ac.za.

Project details

Picornaviruses are an economically important group of pathogens. As the causative agents of various serious diseases (E.g. poliomyelitis, hepatitis, human rhinitis and Foot-and-mouth), they pose a significant threat to the health of humans and economically important livestock. Although many reports describe the epidemiology and pathogenesis of such diseases, the molecular mechanisms by which picornaviruses interact with components of host cells they infect are poorly understood.
It is well established that cells infected with picornaviruses are dramatically altered by the proliferation of cytoplasmic, virus-induced membranous vesicles, which are thought to derive from the cellular secretory pathway. In picornavirus-infected cells, membrane transport from the ER to the Golgi is blocked and the Golgi apparatus disassembles, suggesting that picornavirus infection alters the balance of membrane budding and fusion that is normally maintained between the ER and Golgi compartments. We are proposing that the rearrangement of cell membranes and accumulation of vesicles observed in infected cells arises as a result of specific interactions of viral proteins with the host proteins that control membrane traffic in cells. Using Theiler's murine encephalomyelitis virus (TMEV) as a model picornavirus, this project will use fluorescence and electron microscopy, as well as biochemical assays to investigate the functions of the different non-structural viral proteins and their specific interactions with host cell components.

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University of the Western Cape

Funded Research Positions available in 2008 in the Institute for Microbial Biotechnology and Metagenomics [IMBM], Department of Biotechnology, University of the Western Cape, Cape Town, South Africa.

Several funded positions: senior lecturer, Postdoctoral, PhD and MSc fellowships.

Enquiries should be forwarded to Professor Don Cowan, Director, IMBM (dcowan@uwc.ac.za). Please note that PhD and Masters bursaries can only be awarded to South African citizens.

For the full advert link here.


Cape Peninsular University of Technology

Postdoctoral Fellow - Molecular Biology

Two year contract post

1. Post doc in Molecular Biology with a strong background in Microbiology
2. Proven track record in publications in accredited journals
3. Project information:

a) The stress response of yeast and bacteria to ultrasound. This would be done at the genomic level, possibly using DNA micro-array techniques. In addition, fluorophores will be used to analyse the injury using fluororescent flow cytometry. The aim of this project is to provide fundamental data leading to the application of ultrasound to microbially contaminated beverages in the food industry. Ultrasonics is a powerful alternative to the common disinfection techniques used in the food industry, but little is known about the mechanisms of ultrasonic disinfection, providing more "near to natural" foods. To date, our studies with fluorescent flow cytometry of sonicated and/or heated yeast cells in our well-equipped laboratories has yielded interesting information on the response to these treatments, and we wish to extend the study by considering gene expression during sonication.

b) The provision of edible micro-encapsulated probiotics for incorporation into foods. This is an ongoing study where the aim is to increase the shelf life of probiotics, in particular Bifidobacterium. The latter bacterium has a short shelf-life when incorporated into fermented dairy foods. The isolation of other lactic acid bacteria with probiotic potential is also a possibility. At present, we are pioneering a promising ultrasonic mechanism for generating quantities of micro-capsules for industrial use. This research will include the study of the incorporation into the capsules, substances which enhance survival of the organism. Testing of viability and injury of encapsulated Bifidobacterium will be done using fluorescent flow cytometry. To date, 2 papers have been published on this work.

Both projects can be considered to be biotechnological with important practical industrial applications.

Commencement: January 2008
Remuneration: R120 000 pa

Further enquires can be made by contacting Dr L. McMaster, Dept of Food and Agricultural Sciences, Faculty of Applied Science, Cape Peninsular University of Technology, at McMasterL@cput.ac.za  or on +27 (0) 21-460 3507.

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Rakai Project SAIC - Frederick, Inc

Protocol Coordinator II – Rakai, Uganda - #88867

SAIC-Frederick, Inc., a subsidiary of SAIC, is the Operations and Technical Support Contractor for the National Cancer Institute at Frederick (NCI-Frederick) a federally funded research and development center. SAIC-Frederick, Inc. is one of four related NCI contracts on-site and serves as the infrastructure support for the entire center. The contract is the largest single research contract awarded by the Department of Health and Human Services (DHHS) and it is the department's only Government-owned, contractor-operated facility contract.

SAIC-Frederick, Inc. and our Clinical Research Program are currently searching for a Protocol Coordinator II to provide study coordination services for the Rakai Project, Rakai Health Sciences Program, support to NIAID, located in Rakai, Uganda, including protocol development/ implementation to ensure regulatory compliance from single site to multi-site trials.

The Protocol Coordinator II will be responsible for reporting any Adverse Events to the NIAID IRB, as well as the local Ugandan IRBs. Manages and coordinates intramural sites participating in clinical protocols. Serves as a liaison with personnel at clinical sites in Uganda and the NIAID Principal Investigator. Assists/trains local study staff in explaining the protocol and tests/procedures to the study participants. Provide expertise in data management including data collection, analysis, and writing of interim reports, annual protocol reports, and scientific publications. Manages the quality assurance and quality improvement initiatives specifically involving ICH-GCP. Assists PI during site monitoring visits at intramural sites for auditing protocol conduct. Ensures adequate completion of flow sheets and case reports forms (CRFs). Interacts with auditing and outside sponsors to facilitate data exchange. Conducts updates and training for patient care and research areas on protocol process and progress, human subjects’ protection and quality assurance education. Position is located in Uganda with periodic travel to the U.S. for IRB meetings.

REQUIRED SKILLS: Possession of a Bachelor's degree in a related field or 4 years of related experience in lieu of degree. Master's degree in Public Health (MPH), with a focus on epidemiology and statistics is preferred. Foreign educated candidates who have completed part or all of their education outside of the United States must have their foreign education evaluated by an SAIC-approved accrediting organization to assure that it has met the equivalency of the qualifications of degree work in the United States. In addition to the educational requirement, a minimum of 7 years progressively responsible experience in clinical trials and data management is required. Clinical trials protocol development and data management experience. Ability to effectively interpret ICH-GCPs and educate staff. Ability to work independently and troubleshoot unexpected problems that may arise during the conduct of the trials. Demonstrated knowledge of infectious diseases research, data collection and clinical data report preparation. This position is subject to obtaining a Public Trust Clearance.

DESIRED SKILLS: Prior experience in developing countries preferred.

We offer an excellent salary and benefits program, including medical, dental, and life, 401(k) retirement savings plan, and educational assistance.

For immediate consideration and to see the full job description, please visit our website at www.saic.com  and view position # 88867.


SAIC values diversity in the workplace. EEO M/F/D/V

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Rhodes University

DST/Mintek Nanotechnology Innovation Centre

Postdoctoral Fellowships

Applications are invited for DST/Mintek Nanotechnology Innovation Centre (NIC) - Sensors scholarships (for 2008) for Post-doctoral research in electrochemical and optical sensor technology, based at the NIC at Rhodes University in South Africa.

The aim of the centre is to support research and development of sensor technology for early disease detection and health monitoring.

Postdoctoral applications:
Skill in at least one of the following areas will be advantageous: electrochemistry, AFM, XRD, XPS, QCMD.

Interested applicants are requested to send a full CV to Prof Tebello Nyokong at t.nyokong@ru.ac.za or to Dr Janice Limson by email at j.limson@ru.ac.za.  

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Rhodes University

MSc and PhD Bursaries

MSc and PhD bursaries are available to South African citizens only for study in the Biosensor Research Group of the Department of Biochemistry, Microbiology and Biotechnology at Rhodes University in 2008.

The research group is primarily involved in the design of biosensor technology for environmental, health and agricultural monitoring. 

Interested applicants are requested to send a CV to Dr Janice Limson by email to j.limson@ru.ac.za . For telephonic queries please contact 046 603 8263

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University of the Western Cape

Characterisation of interactions involving the p53-associated protein RBBP6


A Ph.D. and an M.Sc. position are available immediately in the Structural Biology Group in the Biotechnology Department of the University of the Western Cape to investigate novel interactions between the p53-associated protein RBBP6 [1] and proteins which we have recently identified using a yeast 2-hybrid screen. We believe that these interactions will provide important clues to the role of RBBP6 in the control of cancer, including its proposed role in the ubiquitination of p53 [2]. The group has access to excellent facilities for the recombinant production of proteins, for transfection and transduction of tagged proteins into mammalian cell lines, for manipulation of endogenous protein levels using RNAi technology, and for in-vitro analysis of interactions using Nuclear Magnetic Resonance Spectroscopy (NMR) and Isothermal Titration Calorimetry. For structural analysis we have access to a 600MHz NMR spectrometer and a Rigaku X-ray Diffractometer. Candidates should be proficient in the standard techniques of molecular biology and should have an interest in cancer research and/or Structural Biology.

Grant holder-linked bursaries are available from the National Research Foundation under grant FA2007050100005, which are, however, are only available to citizens of South Africa or SADC member countries. Candidates with their own sources of funding are also encouraged to apply. Prospective applicants should email a cover letter, CV and contact email addresses for three referees to Dr David Pugh at the following email address: dpugh@uwc.ac.za

References

1. Reference 1
2. Reference 2

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Rhodes University

Department of Biochemistry, Microbiology and Biotechnology

MSc position

The objective of this research project will be to obtain fundamental molecular data on the plant species of the Valley Bushveld found on the Great Fish River Reserve, and to attempt to identify plant species consumed by herbivores by analysis of their dung. In particular, the research will focus on the dietary preferences of the endangered Black Rhinoceros. The information will be used to assess seasonal dietary preferences, and the level of competition for plant resources between different herbivores.

The candidate should ideally have a biochemistry honours degree, have sound molecular biology skills, and have an interest in environmental and/or wildlife conservation in South Africa.

Contact: Dr Brendan Wilhelmi
E-mail address: b.wilhelmi@ru.ac.za 

Please send a CV by 31 January 2006.

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Rhodes University

Department of Biochemistry, Microbiology and Biotechnology

PhD Position: Picornavirus-host cell interactions

A PhD position will be available in the beginning of 2006 for a doctoral student who has an interest in virus-host interactions. The project is funded by the NRF, and will be supervised by Dr Caroline Knox in the Department of Biochemistry, Microbiology & Biotechnology, Rhodes University. Candidates should have a Masters degree or equivalent qualification, with practical experience in molecular biology, protein biochemistry, cell biology or virology. To comply with the funding conditions, candidates need to be South African citizens or permanent residents. If you are interested, please email your full CV to: caroline.knox@ru.ac.za.

Project details

Picornaviruses are an economically important group of pathogens. As the causative agents of various serious diseases (E.g. poliomyelitis, hepatitis, human rhinitis and Foot-and-mouth), they pose a significant threat to the health of humans and economically important livestock. Although many reports describe the epidemiology and pathogenesis of such diseases, the molecular mechanisms by which picornaviruses interact with components of host cells they infect are poorly understood.
It is well established that cells infected with picornaviruses are dramatically altered by the proliferation of cytoplasmic, virus-induced membranous vesicles, which are thought to derive from the cellular secretory pathway. In picornavirus-infected cells, membrane transport from the ER to the Golgi is blocked and the Golgi apparatus disassembles, suggesting that picornavirus infection alters the balance of membrane budding and fusion that is normally maintained between the ER and Golgi compartments. We are proposing that the rearrangement of cell membranes and accumulation of vesicles observed in infected cells arises as a result of specific interactions of viral proteins with the host proteins that control membrane traffic in cells. Using Theiler's murine encephalomyelitis virus (TMEV) as a model picornavirus, this project will use fluorescence and electron microscopy, as well as biochemical assays to investigate the functions of the different non-structural viral proteins and their specific interactions with host cell components.

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University of the Free State

M.Sc. and Ph.D. bursaries for research in epigenetics, genomics, proteomics and bioinformatics


Laboratory of Epigenomics and DNA Function
Department of Biotechnology
University of the Free State
Bloemfontein

 

A typical human contains enough DNA to span the distance between the sun and the planet Uranus when the DNA in every cell of the body is laid end-to-end. To allow the approximately 2m of DNA present in a single cell to fit into the cell nucleus of approximately 10mm diameter requires the DNA to undergo a significant degree of compaction. This is achieved by packaging the DNA into chromatin, which is formed by a repetitive array of nucleosomes, each formed by a histone octamer onto which approximately 168bp of DNA is wound. The ends of the nucleosomal DNA loop are sealed by linker histone H1, allowing more compacted structures. Although this solves the problem of fitting the DNA into the cell nucleus, the packaging also masks the DNA molecule from other DNA-binding proteins involved in DNA functions such as gene expression, DNA replication, recombination and repair. The eukaryotic cell has evolved several mechanism to regulate the decondensation or "unmasking" of the DNA molecule to allow such essential processes, including ATP-dependent chromatin remodelers and covalent modifications to the core histones. In the Laboratory of Epigenomics and DNA Function we study this relationship between chromatin structure and gene expression (epigenetics) on a genome-wide scale. Most of our work is performed in the unicellular eukaryote Saccharomyces cerevisiae, which can easily be genetically modified, and for which the entire genome has been sequenced. The following research projects leading to M.Sc. and Ph.D. degrees are currently available in the laboratory:

· Does covalently modification of H1 regulate its binding to chromatin?
This project will investigate possible changes in the modification state of linker histone H1 when bound to chromatin, and will make use of molecular biology and proteomic techniques.
· Is H1 binding to chromatin regulated by core histone modifications?
This project will investigate the possible change in the modification status of the core histones when H1 is bound to chromatin, and will make use of molecular biological and proteomic techniques.
· What is the relationship between chromatin modification status and compaction?
This project will investigate the degree of condensation of chromatin on a genome-wide scale as a function of H1 binding, and will make use of molecular biological and genomic techniques such and gene expression microarrays.
· What is the role of the core histone N-terminal tails in chromatin compaction in living cells?
This project will investigate the compaction state of chromatin in yeast cells as a function of the N-terminal tails of the four core histones, and will make use of molecule biological, biochemical and genomic techniques.
· What directs different H1 isotypes to different genomic locations in the mouse genome?
This project will investigate the core histone modification state in different regions of the mouse genome accommodating different H1 variants, and will make use of molecular biological and proteomic techniques.
· The development of software for the analysis of physical gene clustering in human, Drosophila and Arabidopsis genomes.
We have previously developed a program to analyze physical clustering in the yeast genome. This program will be expanded to allow the analysis of other genomes as well, and the project will involve coding and bioinformatic development.

Interested candidates are encouraged to contact Prof. Hugh Patterton (e-mail patterh.sci@mail.uovs.ac.za - telephone 051-4012274) for further information.
2 M.Sc. and 2 Ph.D. bursaries are available.


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University of the Free State/University of Cape Town



Post-doctoral position available at the University of the Free State / University of Cape Town  - Collaborative research within the Alkane Activation Programme of the Centre of Excellence in Catalysis

The primary aim of this project will be to compare different alkane hydroxylase systems in order to develop optimal biocatalysts and biomimetic catalysts for the hydroxylation of alkanes. Experience or an interest to gain experience in enzyme isolation and characterization, protein modelling and genetic engineering is required. Previous experience in working on P450 or diiron monooxygenases will be a strong recommendation.

The successful candidate will shuttle between the Department of Microbial, Biochemical and Food Biotechnology at the University of the Free and the Department of Chemical Engineering, University of Cape Town.

Renumeration for this position is R110 000 per annum (not subject to
tax). Preferred starting date is January 2006 or soon as possible after.

Contact: Prof. Martie Smit
e-mail: smitms.sci@mail.uovs.ac.za 
tel: +27-51-4012219
or
Prof. Sue Harrison
e-mail: stlh@chemeng.uct.ac.za 
tel: +27-21-6504021


 

University of the Free State, BIOPAD, NRF

PhD bursaries in Biotechnology open for application.

Enter here for more detail.

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Rhodes University

Department of Biochemistry Microbiology and Biotechnology

PhD/MSc Position

The role of molecular chaperones in the self-renewal of stem cells

A PhD or MSc position is available for a suitably qualified South African, preferably from the designated groups, to join a research team investigating the molecular and cell biology of stem cells. This research project is part of a multidisciplinary Rhodes University Research Group studying "Biomolecular Interactions", and is funded as part of an NRF Research Niche Area Programme. The project will be carried out in the Molecular Chaperone Research Laboratory under the joint supervision of Prof Greg Blatch and Dr Earl Prinsloo. There are various ongoing projects investigating the role of molecular chaperones (Hop, Hsp70 and Hsp90) in the maintenance and differentiation of embryonic stems cells, with particular emphasis on the STAT3 signal transduction pathway.

The deadline for applications is 30 November 2007, and eligible candidates should send a full CV and letter of motivation to Prof Greg Blatch (Tel: +27-46-603-8262; Fax: +27-46-622-3984; Email: G.Blatch@ru.ac.za  Website: http://www.ru.ac.za/blatch ).

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University of Cape Town

MSc Position

Project: Sociogenetic structure of the endemic fynbos ant, Camponotus klugii

The primary aim of this project is to use microsatellite DNA markers to elucidate the colony genetic structure of the endemic fynbos ant species Camponotus klugii, and to evaluate the hypothesis that nest-site limitation in the fynbos may be a major ecological constraint shaping the sociogenetic organisation of C. klugii colonies.

Applications are invited from enthusiastic and suitably qualified South African students for a MSc research project funded by the National Research Foundation. Work will be carried out in the Molecular and Cell Biology Department of the University of Cape Town. This project will be supported by a NRF Grantholders -linked bursary, as well as project running costs.

This project will be supervised by Dr Colleen; Ryan (UCT) and Geeta Eick (US), in collaboration with Dr Hamish Robertson of the South African Museum, Cape Town.

For further details, please contact Geeta Eick (eick@sun.ac.za, Tel: 021-808 3229) or Colleen O Ryan (colleen@science.uct.ac.za Tel: 021 650 4257).

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Advanced Research Centre for Applied Microbiology 

University of the Western Cape, Cape Town, SA

MSc, PhD and Post-Doctoral Research positions for 2007 

The ADVANCED RESEARCH CENTRE FOR APPLIED MICROBIOLOGY (ARCAM), headed by Professor DA Cowan, is a major research unit in the Department of Biotechnology at UWC. ARCAM is sited in a new 450m2 state-of-the-art research laboratory, and currently comprises 30 staff, including 8 post-doctoral, 9 PhD and 6 MSc researchers. The group publishes extensively in international journals.

Positions available immediately:
3 x Post-Doctoral fellowships
3 x PhD positions
2 Masters positions

PLEASE NOTE: ONLY SA CITIZENS AND MEMBERS OF SADEC COUNTRIES ARE ELIGIBLE FOR NRF PHD BURSARIES.

1. Engineering Thermophilic Bacteria for Bioethanol Production
[1 x POST-DOCTORAL POSITION]
[1 x PhD position]
ARCAM has recently established a 5-year collaborative project with a European Biotechnology company. We are seeking a senior Post-Doctoral candidate to lead a team of researchers investigating the metabolic engineering of thermophilic bioethanol-producing organisms. Applicants should be experienced prokaryotic molecular geneticists. Experience in proteomic and microarray techniques would be an advantage. PhD applicants should have a strong background in molecular genetics and microbiology.

2. Exploiting Extremophile Genome Diversity
[2 x PhD POSITIONS]
[2 x Masters position]
ARCAM is strongly supported by the NRF under the HBU-RDP program. This 5-year program, which incorporates a range of projects including the microbial phylogenetics of Antarctic psychrophilic and New Zealand, Chinese and Chilean hydrothermal biotopes, the development of new gene mining methods, and the structural and functional analysis of novel extremophilic enzymes, currently supports two Post-Doctoral and 3 PhD researchers. Two additional PhD and two MSc posts are available to strong applicants with interests in molecular ecology and/or protein structure/function.

3. Microbiology of Acid Mine Drainage remediation systems.
[1 x POST-DOCTORAL POSITION]
Researchers with experience and interest in microbial ecology are required to contribute to an ESKOM/WRC-funded project investigating the microbial diversity of bioremediation systems employing alkaline Fly Ash to treat Acid Mine Drainage.

4. Genomics of Hyperthermophiles.
[1 x POST-DOCTORAL POSITION]
In a project funded by the National Bioinformatics Network (NBN) through the UWC Node, we are seeking an experienced Bioinformaticist to contribute to our work on hyperthermophile genomics.

It is ARCAM policy that Post-Doctoral bursaries (which are not subject to tax) are offered at a minimum level of R85,000 per annum. These bursaries are open to applicants of all nationalities. We may provide some travel and accommodation assistance to successful overseas applicants. PhD bursaries are offered at a minimum of R50,000. Please note that only SA citizens and members of SADEK countries are eligible for NRF PhD bursaries.
More information on the activities of the UWC ARCAM laboratory is available on: http://www.biotechnology.uwc.ac.za/Research/ARCAM/arcamindex.htm
 

All enquiries and applications should be directed to:
Professor DA Cowan, Department of Biotechnology. University of the Western Cape, Bellville 7535, Cape Town, South Africa
Tel: +27 (0)21 959 2083 Fax: +27 (0)21 959 3505 E-mail: dcowan@uwc.ac.za

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University of Cape Town

RESEARCH POSITIONS OFFERED
IN BIOCATALYSIS AND BIOREMEDIATION

Applications are invited from prospective at Postdoctoral research fellows, to work in a highly active research group, in a multidisciplinary Biotechnology-related field.

Biocatalysis is a relatively new, and rapidly developing field of Biotechnology, where chemical products are developed by exploiting the well-recognised efficiency of biological processes.

The research field encompasses aspects of chemistry, biochemistry, microbiology and biotechnology, in innovative approaches to the development of commercial biotechnological processes. Researchers within the group may focus in specific areas such as applied enzymology, microbiology, or biochemical processing. There will be opportunities to work in collaboration with established international experts in a range of areas, and to develop their own expertise in modern and novel areas.

The work will be conducted under the coordination of Dr Stephanie G Burton, within the broader framework of an actively collaborating group of academic researchers at various universities and technikons in the Western Cape, involving chemical engineers, microbiologist, biochemists and biotechnologists, and with affiliation to the Cape Biotech Initiative (CBI) and the Advanced Research Centre for Applied Microbiology (ARCAM). Bursary funding is available through established research grants from a number of funding organizations.

To apply, please submit a CV and the names and addresses (including e-mail)
of two referees, to: Dr S G Burton
Biochemical Processing Group
Department of Chemical Engineering
University of Cape Town
Cape Town 7701

E-mail: Sburton@chemeng.uct.ac.za 

Phone: 021 6502516 Fax: 021 689 7579

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University of Cape Town

The following positions are available immediately in the dynamic multidisciplinary
Bioprocess Engineering Research Unit within the Chemical Engineering Department at
University of Cape Town:
* Postdoctoral
* Doctoral (PhD)

The project centres on determining population shifts in sulphate reducing populations
as a function of environmental conditions encountered in the active sulphate reduction
process. The shifts in population are to be determined using molecular probe techniques,
including FISH. The project forms part of a broader project, within the unit, focused
on environmental bioremediation with specific interest in metal sulphate wastes such as
acid mine drainage and the anaerobic treatment thereof.

Renumeration for the postdoctoral position is R80000 per annum, with the possibility of
a tax exemption. Bursaries will be arranged for the PhD candidates.

Applicants with suitable qualifications in molecular biology and/or microbiology and chemical engineering (experience in molecular probe techniques will be advantageous) are invited to forward a CV, two referees and a letter of application to Prof Sue Harrison.

Prof Sue Harrison
STLH@chemeng.uct.ac.za
Fax (021) 6897579

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Post-doctoral Fellowships at the University of Cape Town

Chromatin Structure and the Regulation of Gene Expression

It is well established that chromatin is involved in the regulation of multiple genetic processes, including transcription, replication and recombination. This regulation occurs by differentially exposing the DNA molecule during discrete structural transitions in chromatin, facilitated by post-translational modifications of the core and linker histones as well as by ATP-dependent chromatin remodeling complexes. We study these regulatory mechanisms in Saccharomyces cerevisiae, which provides a powerful experimental system of which the entire genome sequence is available, and that can readily be genetically modified.

Post-doctoral fellowships are available to investigate aspects of the binding, role and dynamic genomic distribution of linker histone H1 during extensive transcriptional reprogramming in yeast.

The positions are available immediately, and applications will be accepted until they are filled. The successful applicant will hold a Ph.D. degree in biochemistry or a related field, awarded within the last 5 years.

Please submit a cover letter, CV and the name and contact details of three referees to Dr. Hugh Patterton, Department of Molecular and Cell Biology, University of Cape Town, University Private Bag, Rondebosch 7700, Telephone 021-650-3267, FAX 021-689-7573, E-mail: patterh@science.uct.ac.za., Web: http://www.dnassist.org/patterton/patterton.htm.

Cape Town is a modern, cosmopolitan city, nested at the foot of Table Mountain and with easy access to beautiful beaches, mountains and surrounding Nature areas. More information is available at http://www.capetourism.org.

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UNIVERSITY OF CAPE TOWN / UNIVERSITY OF THE WESTERN CAPE

Masters in Structural Biology

 

· A new programme in a challenging and stimulating field

· Structured around internationally acclaimed courseware

· Superbly resourced

· Programme mounted by seventeen scientists at UCT, UWC and US.

· Seven internationally acclaimed foreign scientists will interact directly with the students

· International job opportunities

· Bursaries of R27000 per annum for suitable candidates

· Research projects in the fields of HIV, Hypertension, Cancer, industrial enzymology etc.

Structural Biology provides an understanding of the functions of biological macromolecules and cells in terms of their three dimensional structures. It underpins the development of key aspects of Biotechnology, a priority area for South Africa, which includes rational drug design and the design of enzymes for industrial purposes.

The Joint UCT/UWC Masters in Structural Biology involves a year of coursework and a year of research. It commences in February 2003. Students will have access to resources at both UCT and UWC. The focus of the programme will be the determination of biological structure using X-ray crystallography, NMR spectroscopy, electron microscopy and computer modelling. The coursework will lay the foundations for research in structural biology and will range from molecular and cell biology to topics in bioinformatics, computer programming and protein chemistry. The class size will be limited and applications will be judged on the basis of academic merit and appropriate experience. An equivalent of a four year undergraduate degree in fields including but are not limited to Biochemistry, Physics, Chemistry, Molecular and Cell Biology, Informatics and Engineering is a prerequisite. Generous financial assistance is available to suitable candidates. Applications should be submitted immediately.

Further information is available at http://sbio.uct.ac.za

Enquiries should be sent to : Postgraduate Admin Officer, Faculty of Health Sciences, UCT Medical School, Anzio Road, Observatory 7925, South Africa.

Email: mdevries@curie.uct.ac.za Telephone: +27 21 406 6340

This programme was made possible by a grant from the Carnegie Corporation of New York. The statements made and views expressed are solely the responsibility of the authors.

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University of Cape Town

UNIQUE OPPORTUNITIES TO STUDY THREATENED & ENDEMIC GOLDEN MOLES AT A WORLD-CLASS AFRICAN UNIVERSITY!

Applications are invited from suitably qualified South African students for two M.Sc research projects funded by the National Research Foundation, and hosted jointly by the Departments of Zoology and Cell & Molecular Biology, at the University of Cape Town. Each project will be supported by a NRF bursary of R14000 p.a. (for a maximum of 2 years), plus field and laboratory running costs. Top-up bursary funds may be made available on a merit basis. Only candidates with a valid RSA driver's licence will be considered. Previous experience in either fieldwork on small mammals, or laboratory-based genetics methodologies, will be advantageous.

Conservation genetics, population variation and differentiation of the endangered Giant golden mole (Chrysospalax trevelyani).

The Giant golden mole is restricted to Afromontane forests of Eastern Cape, from the Amathole Mountains north-eastwards through Transkei to Port St. Johns. Owing to fragmentation of these forests, habitat degradation as a result of harvesting firewood and ring-barking of trees, and hunting by feral dogs, many populations appear to have been severely impacted, and this species may be extinct in many parts of its former range. There have not, however, been any recent surveys of this species, or any objective assessment of the viability of remaining populations.

Literature on the ecology of this species is mostly anecdotal, and little is known of breeding in this species except that litter sizes are small and that post-natal care is extended, suggesting a K-selected reproductive strategy. There is, therefore, a clear need for more information on the ecology, reproductive biology and biogeography of remaining demes to assess their ecological and genetic viability and facilitate the effective management of this endangered species.

This project forms part of a broader research programme on the conservation biology of giant golden moles, and will involve extensive fieldwork to survey all localities where C. trevelyani has been previously collected, as well as selected intermediate indigenous forest patches. Depending on the research qualifications and experience of the candidate, the project may be tailored to have either an ecological or genetics emphasis. The ecological component will entail monitoring one population, located in a protected area (to minimize extraneous disturbance factors), to determine generation times, age and sex structure, and reproductive parameters such as breeding periodicity, gestation period, litter sizes and the length of post-natal development. Alternatively, the genetic component will focus on molecular analyses of samples (toe-clippings) obtained by non-destructive means to investigate population structuring and effective population sizes using microsatellite loci. Microsatellite loci in giant golden moles will have to isolated because there are no primers available. Thus, the first step in this programme will be the construction of such a library, requiring a candidate with a strong biochemical background.

The genetic, distributional and\or demographic data suites will then be integrated to determine effective population sizes and results will form the basis of recommendations for the effective and applied conservation and management of existing populations.
The successful incumbent will be assisted (on a part-time basis) in the field by a postgraduate student from the Department of Zoology at University of Fort Hare. The potential for upgrading of the M.Sc study to a Ph.D. also exists, and will be considered contingent upon suitable progress during the first year of study.

Phylogeography and systematics of the golden mole genus Chrysochloris in South Africa.

The genus Chrysochloris includes 2 species endemic to South Africa, namely the the Cape golden mole (C. asiatica), widespread in the Fynbos and Nama-Karoo biomes, and Visagie s golden mole (C. visagiei), a Critically-Endangered species known from only Calvinia in Succulant Karoo of Northern Cape. The systematic and conservation status of these taxa remain abstruse owing to a lack of information on geographic variation in morphological and genetic characteristics.

The range of C. asiatica coincides with the Cape fold mountains, which may act as barriers to dispersal and gene flow, leading to high levels of differentiation among fragmented populations, and perhaps even the existence of cryptic species. Based on marked geographic variation in size and fur colour in C. asiatica, up to 8 subspecies have been proposed, but the most recent regional taxonomic revisions treated this species as monotypic on the grounds that clines may be involved. A proper understanding of the nature and extent of geographic variation in phenotypic and genetic characteristics, and patterns of gene flow between demes, are contingent upon detailed analyses of populations from throughout the range of the species.

This project will also clarify the systematic and conservation status of Visagie s golden mole (Chrysochloris visagiei), known from only a holotype collected near Calvinia, which some authors consider to be only an aberrant C. asiatica. Further research is clearly needed to establish if this taxon does indeed occur in the Calvinia district, and to clarify its systematic before its true conservation status will become clear.

This project will form part of a broader research programme that will employ morphometric analyses based on existing museum specimens, as well as extensive fieldwork to acquire samples (using non-destructive methods) for chromosome and genetic analyses. Inter-population differentiation will be examined using sequence data from the cytochrome-b mitochondrial DNA genome, after amplification using suitable primers. Phylogeographic analyses of chromosomal and genetic data, together with cladistic analysis of morphometric characters, will enhance our understanding of micro-evolutionary patterns among these taxa, and how these relate to theories on phylogenetic divergence and speciation in fossorial mammals, which are based largely on subterranean rodents. Given the wide scope of this research programme, this M.Sc study may be tailored to suit the research preferences of the successful candidate, with greater emphasis on either fieldwork and systematics, or laboratory-based genetics methodologies. The potential for upgrading of the M.Sc study to a Ph.D. also exists, and will be considered contingent upon suitable progress during the first year of study.

For further details, please contact either:

Dr Gary Bronner, Dept. of Zoology; Ph: 021-6503650; email: gbronner@botzoo.uct.ac.za OR

Dr Colleen O Ryan, Dept. of Cell & Molecular Biology; Ph: 021-6504257; colleen@science.uct.ac.za; at the University of Cape Town, P/Bag Rondebosch, 7701, South Africa.

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MSc/PhD Opportunities at the University of Natal, Pietermaritzburg

***Bursaries of R14,000 - R30,000 are available***

RESEARCH PROJECTS :
1. Conservation genetics of the Karkloof Blue butterfly and relatives (Orachrysops species)
2. Phylogeography of sugarcane stemborers Eldana saccharina and Chilo sacchariphagus
3. Biotype identification in parasitoids of African cereal stemborers
4. Empirical investigation of the genetic species concept in insects
[computer-based project]

For further information see http://www.nu.ac.za/biogen/postgrad.htm

Contact:
Dr A Mitchell
E-mail: mitchellA@nu.ac.za
Phone: 033 260-5815

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Rhodes University

MSc and PhD Positions Available

Projects related to enzyme synergy and biofuel production are ongoing and currently available in the Cellulosome Research Group (CRG):

Cellulosomes consist of discrete multi-functional, multi-enzyme complexes wherein all the enzymatic factors leading to cellulose degradation are physically attached to a central scaffold component. Biofuel technology is rapidly regaining popularity and the clostridial cellulosome is believed to play a key role in this field. The activities of cellulosomes are a key consideration for the subsequent production of compounds such as acetone, butanol and ethanol (ABE) from biomassic waste such as corn stover, bagasse, etc. The aim of the project is 1) to examine the synergy that exists between cellulases and hemicellulases for the efficient breakdown of complex biomassic substrates to reducing sugars and 2) to construct suitable bioreactors to produce biofuel from various biomassic substrates and to perform a temporal study of the bioreactor environment, monitoring cellulosome activity, pH and the production of ABE (acetone, butanol and ethanol) compounds. The following parameters will be monitored according to established methods over time: clostridial CFU, cellulosome activities, VFA (volatile fatty acids-total and composition: acetic, butyric and propanoic) (GC) and pH, ABE content and total reducing sugar content (by Somogyi-Nelson or dinitrosalicylic (DNS) method) and reducing sugar type.

Applications are invited from enthusiastic and suitably qualified (i.e. prior expertise in enzymology, molecular biology or cellulase/cellulosome research) South African and international students for a MSc, PhD or Postdoctoral research project funded by various Industrial research grants and the National Research Foundation (NRF). This research work will be carried out in the Department of Biochemistry, Microbiology and Biotechnology at Rhodes University , Grahamstown.

Research for this project will be conducted under the supervision of Dr Brett Pletschke, in collaboration with various researchers abroad based in the U.S.A. , France and Japan .

For further details, please contact Brett Pletschke (E-mail: B.Pletschke@ru.ac.za  or Tel: 046-603 8081). To apply, please submit an updated CV to e-mail: B.Pletschke@ru.ac.za

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Phylogeography And Colonisation Histories Of Invertebrate Species On Sub-Antarctic Marion Island.

MSc or PhD position

Advances in modern molecular techniques are allowing investigations into the phylogenetic relationships, phylogeography, and colonization history of taxa on the sub-Antarctic islands. The sub-Antarctic islands are recognised as areas of significant research and conservation value with an immense potential for contributing to our understanding of biological processes. However, virtually nothing is known about the geographical and temporal distribution of genetic variability, or the colonization patterns, on these islands. Our research group uses sequence data from mitochondrial and nuclear genes to address questions relating to the population history of taxa from Marion Island and other sub-Antarctic islands.

If you are looking for an exciting post-graduate research opportunity then why not join us. Current funding is available for either an MSc (annual bursary of R35 000) or PhD (annual bursary R45 000) student interested in research within this programme. The research will be conducted under supervision in the Molecular Laboratory in the Department of Zoology, University of Stellenbosch, with fieldwork undertaken on Marion Island, the jewel of the Southern Ocean!

Send your Curriculum Vita, proof of academic record and the contact details of two academic referees to either:

Dr Savel Daniels
Tel: (021) 808 3230
Email: srd@sun.ac.za

Dr Bettine Jansen van Vuuren
Tel: (021) 808 4862
Email: bjvv@sun.ac.za

Department of Zoology; Private Bag X1; Matieland 7602
Fax: (021) 808 2405

http://www.sun.ac.za/zoology/mollab

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Stellenbosch University

MSc Postgraduate study

Opportunity for MSc study on the development of a phytoestrogen product from honeybush with enhanced estrogenic potency for the nutraceutical market.

Honeybush tea contains phenolic compounds with phytoestrogenic activity (compounds that exhibit estrogen-like activity) and exploitation of this property would enable the South African nutraceutical industry to compete internationally with a unique South African phytoestrogen product.

Our laboratory recently showed that both aqueous and methanol fractions from selected honeybush species bind to the estrogen receptor. Current work in our laboratory on this project focuses on interactions with both the alpha and beta isoforms of the estrogen receptor and induction of estrogenic effects through investigation of synthetic and endogenous promoters containing estrogen responsive elements as well as more complex estrogen induced effects such as cell proliferation where effects of several genes are involved.

This MSc project will, however, focus on determining the binding of honeybush fractions to sex hormone binding globulin (SHBG) (saturation binding, competitive binding and percentage free steroid assays) and their effects on SHBG levels (SHBG promoter-reporter assays, determination of mRNA and protein levels). Estrogenic compounds are transported in the blood bound to the high affinity binding globulin, SHBG, and only a small percentage is free and biologically active. Thus the dynamic equilibrium of different estrogenic compounds, including phytoestrogens, between the extracellular and intracellular compartments that reflects the true biological situation is finally determined by extent of binding to SHBG and direct effects on SHBG synthesis. This is an extremely exciting new project as most in vitro screening systems have not addressed the crucial question of biological availability of phytoestrogens as determined by binding to SHBG or effects on SHBG levels.

The research will be carried out at two institutions, the Department of Biochemistry at the University of Stellenbosch and the Post-Harvest & Wine Technology Division of ARC Infruitec-Nietvoorbij with Dr Ann Louw as promoter and Dr Lizette Joubert as copromoter. A NRF MSc bursary is available.

Candidates can apply by sending their CV to Dr Ann Louw al@sun.ac.za

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University of Cape Town

The MRC/UCT Research Group for Receptor Biology

Post-Doctoral Position

The MRC/UCT Research Group for Receptor Biology at the Institute for Infectious Disease and Molecular Medicine, Faculty of Health Sciences is seeking a Post-Doctoral Fellow.

A competitive Fellowship will be awarded to the successful candidate

The Group's research focuses on the G protein-coupled receptor family, with emphasis on receptors that are important for reproductive health. The group is studying function and signalling of gonadotropin-releasing hormone receptors, role of cyclooxygenases and prostaglandins in cervical cancer and the interaction of HIV with the human CCR5 receptor.

To apply: Applicants should submit a curriculum vitae including the names, telephone numbers and e-mail addresses of two referees to:
Prof. Arieh Katz
IIDMM
Faculty of Health Sciences
University of Cape Town
Anzio Rd. Observatory 7925
Fax: 021-406 6061
E-mail: arieh.katz@uct.ac.za 


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University of KwaZulu Natal              CSIR Environmentek

Research Positions/Scholarships

A number of scholarships are available for students to undertake a variety of exciting M.Sc., Ph.D., and Postdoctoral research projects through the CSIR/University of KwaZulu-Natal Forestry and Forest Products Research Centre (ffp). The scholarships will be awarded on a competitive basis to suitable candidates.

ffp is a joint venture between the Division of Water, Environment and Forestry Technology of the CSIR and the University of KwaZulu-Natal (UKZN) and is closely aligned with the research needs and priorities of the forestry, pulp and paper industry.
Students with the following backgrounds are encouraged to apply: Chemical Engineering, Chemistry, Applied Chemistry, Applied Maths, Biology, Information Technology, Environmental Science, Remote Sensing, Forestry, and Statistics.

A minimum of an Honours or a 4 year degree is required for M.Sc. scholarships.

Projects are in hand and planned as from February 2005 in the following areas:

· Biology and Wood Science
· Xylem Development
· Pulp and Paper Processing
· Wood Chemistry
· Remote Sensing in Forestry

For more information, please see http://ffp.csir.co.za  or contact

Dr Fethi Ahmed
Tel (031) 242 2315
Fax (031) 261 1216
E-mail fahmed@csir.co.za 

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RHODES UNIVERSITY
DEPARTMENT OF BIOCHEMISTRY, MICROBIOLOGY & BIOTECHNOLOGY
SOUTH AFRICA

NATIONAL BIOINFORMATICS NETWORK (NBN)

BIOINFORMATICIST

Three (3) year contract position at the level of Junior Lecturer/Lecturer

As a newly established node within the National Bioinformatics Network (NBN), we wish to appoint a bioinformaticist who would play a key role in the development of bioinformatics teaching and research at Rhodes University. The successful candidate would also be responsible for developing course curricula in collaboration with the National Bioinformatics Network (NBN). A PhD in bioinformatics is the minimum qualification for the lecturer position, while an MSc in bioinformatics with at least two years experience in teaching and research is the minimum qualification for the junior lecturer position.

A salary package will be offered within the university scales and according to the level of the appointment. The selection process will commence on Friday 27 May, and will continue until a suitable candidate is appointed or a decision is taken not to fill the post.

Application forms are available at http://www.ru.ac.za/jobs, by phoning 046-603-8115/603-8004 or by emailing A.Orsmond@ru.ac.za. Curricula vitae, which are not accompanied by an official Rhodes University application form, will regretfully be returned to candidates. For further details visit the following web pages: www.nbn.ac.za/Nodes/ru_node.html and www.ru.ac.za/academic/departments/biochem 

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University of Cape Town

Post-Doctoral Position

The MRC/UCT Research Group for Receptor Biology

The MRC/UCT Research Group for Receptor Biology at the Institute for Infectious Disease and Molecular Medicine, Faculty of Health Sciences is seeking a Post-Doctoral Fellow. A competitive Fellowship will be awarded to the successful candidate.

The Group's research focuses on the G protein-coupled receptor family, with emphasis on receptors that are important for reproductive health. The group is studying function and signalling of gonadotropin-releasing hormone receptors, role of cyclooxygenases and prostaglandins in cervical cancer and the interaction of HIV with the human CCR5 receptor.

To apply: Applicants should submit a curriculum vitae including the names, telephone numbers and e-mail addresses of two referees to:
Prof. Arieh Katz
IIDMM
Faculty of Health Sciences
University of Cape Town
Anzio Rd. Observatory 7925
Fax: 021-406 6061
E-mail: Katz@curie.uct.ac.za 

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University of the Western Cape
Cape Town, South Africa

2 MSc positions for 2006
 
Investigating the molecular interaction between coronavirus NL63
proteins and host proteins.

Two NRF funded MSc positions are available for candidates with basic experience in microbiology, molecular biology and/or cell culturing techniques. Applications are invited from suitably qualified South African candidates or of SADC member countries.

PROJECT 1:
The primary focus of this project is to investigate the molecular interaction between human coronavirus NL-63 (HCoV-NL63) structural protein M and host proteins, using Yeast two hybrid screening and immunoprecipitation assays. Also, the effect of overexpression of M on cell function and the in vitro processing of M will be studied.

PROJECT 2:
The primary focus of this project is to investigate the molecular interaction between human the coronavirus NL-63 (HCoV-NL63) accessory protein and host proteins, using Yeast two hybrid screening and immunoprecipitation assays. Also, the effect of overexpression of the accessory protein on cell function will be studied. The in vitro
processing of the accessory protein will be studied.

For further details please contact Dr B. Fielding.

The deadline for applications is 30 November 2006. Eligible candidates should send a complete CV to Dr Fielding. Note that only successful candidates will be contacted and positions should be filled by December 2006.

Dr B.C. Fielding
Department of Medical BioSciences
E-mail address: bfielding@uwc.ac.za 

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University of Cape Town

Biocatalysis Research Group
Bioprocess Engineering Research Unit

Department of Chemical Engineering

Information:
Opportunities exist for suitably qualified individuals to join a dynamic research team to work in up to 3 year contract research positions:

1) Postdoctoral fellows or Scientific Officers

Researchers are required who will make a significant contribution to the leadership and activities of the research group including:
i) contributing to the research productivity in contract research projects involving, among others, fermentation, biochemical and chemical analysis;
ii) offering leadership and supervisory guidance to postgraduate students working on projects within the group;
iii) interaction with the research group leader to assist with organization within the research group and the laboratory
iv) contribution to, and co-authoring of, research publications.

For a Postdoctoral Fellowship, the successful applicant should have a recently completed PhD in Chemistry, Biochemistry, Microbiology or Chemical Engineering and must have experience in academic writing.

For a Scientific Officer, the successful applicant should have a Masters or PhD in Chemistry, Biochemistry, Microbiology or Chemical Engineering or equivalent qualification, and must have some experience in working in the relevant field, preferably but not necessarily in an academic environment.

2) Contract researcher

An opportunity for a contract researcher to undertake laboratory work contributing to the research activities of the research group, particularly involving fermentation and biochemical and chemical analysis. Options may include part-time postgraduate study toward a higher degree.
Suitable applicants may hold BTech or BSc degrees.

PROJECTS INCLUDE:

1. Routes to Energy from wastewater
2. Bioremediation and beneficiation of agricultural wastes
3. Development of wetlands for bioremediation
4. Biocatalysis to produce biologically active molecules

Contact
Prof. Stephanie Burton 
Stephanie.Burton@uct.ac.za
 
Phone:+27 21 6502516
Fax: +27 21 650 5501

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